A Molecular and Cellular View of Protein Kinase CK2

A Molecular and Cellular View of Protein Kinase CK2

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It is now generally recognized that protein kinase signaling is involved in virtually every aspect of cell function, including growth and proliferation. The field of protein phosphorylation, including the enzymes involved in this post-translational modification, continues to advance at a fascinating pace. Since the first international meeting on this topic, held in Heidelberg in 1994, several new avenues of CK2 research have emerged despite persistent deficiencies in our understanding of the regulation of its activity. Among the significant new directions are studies related to the structure of the enzyme, especially its crystal structure, as well as an interesting aspect of CK2 function that involves its subunits as binding partners of several other proteins. In addition, new data have been gathered on the role of CK2 in transcription as well as in certain other cellular functions. To address these various aspects of the progress of CK2, a number of key scientists from different parts of the world came together at the second international meeting on `A Molecular and Cellular View of Protein Kinase CK2', held at Villard de Lans near Grenoble on September 24-26, 1997. The meeting was attended by nearly 50 participants and included 28 presentations, which provide a view of the latest progress on protein kinase CK2.Acknowledgments We are very thankful to Mrs. Lynda Munar for maintenance of cell cultures and help with baculoviruses purification and ... Hathaway GM, Traugh JA: Casein Kinases-multipotential protein kinases. ... Cell Mol Biol Res 40 : 373-381, 1994 ManiatisT, Fritsch EF, Sambrook J. Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory ... Cell Mol Biol Res 40: 383a€“ 390, 1994 2.

Title:A Molecular and Cellular View of Protein Kinase CK2
Author: Khalil Ahmed, E. Chambaz, Olaf-Georg Issinger
Publisher:Springer Science & Business Media - 2012-09-18

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