Microbial Genomics and Drug Discovery

Microbial Genomics and Drug Discovery

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Exploring innovative routes of drug discovery in the postgenomic era, Microbial Genomics and Drug Discovery examines bioinformatic and genomic approaches for the identification, detection, selection, and validation of new antibacterial targets and vaccine candidates. The book discusses potential pathways for effective infection control, inhibition of antibacterial resistance, and acceleration of the drug discovery process. This comprehensive reference describes procedures to recognize common targets in various bacterial species for the design of broad-spectrum antibiotics and clearly illustrates the use of pathway tools in a genomics-based drug discovery project.Clostridium. In: PR Murray, EJBaron, MA Pfaller, FC Tenover, and RH Yolken, eds. Manual of Clinical Microbiology, 7th edition. Amer Society for Microbiology, 1999. S De Baets, K Mortelmans. SIM News 51:125-131, 2001. FR Blattner et al.

Title:Microbial Genomics and Drug Discovery
Author: Thomas J. Dougherty, Steven J. Projan
Publisher:CRC Press - 2003-05-14

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